Table 1.
Analysis of the methylation status of six CpG sites in the ESRRG promoter for laryngeal squamous cell carcinoma (LSCC) tumor and normal tissues
| CpG sites | Tumor tissue (Mean ± SD) | Normal tissue (Mean ± SD) | P value |
|---|---|---|---|
| CpG1 (%) | 40.47 ± 14.23 | 24.25 ± 10.81 | <0.01 |
| CpG2 (%) | 34.16 ± 14.25 | 20.99 ± 12.72 | <0.01 |
| CpG3 (%) | 34.81 ± 15.07 | 21.58 ± 11.97 | <0.01 |
| CpG4 (%) | 34.88 ± 15.54 | 19.34 ± 11.30 | <0.01 |
| CpG5 (%) | 39.88 ± 14.81 | 25.97 ± 11.76 | <0.01 |
| CpG6 (%) | 32.88 ± 17.07 | 14.52 ± 6.87 | <0.01 |
| MIa (%) | 36.18 ± 14.54 | 21.11 ± 10.45 | <0.01 |
a
MI, methylation index, calculated as the mean methylation status of the six CpG sites analyzed.