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. 2019 Jul 2;116(29):14448–14455. doi: 10.1073/pnas.1814271116

Fig. 4.

Fig. 4.

Effects of actomyosin contractility inhibitor blebbistatin on intracellular and extracellular mechanics. (A–C) Log2 ratios of intracellular vs. extracellular |G*(ω)| for MCF10-CA1 cells (A), MCF7 cells (B), and D2.A1 cells (C) embedded in 3D lrECM treated with blebbistatin. (D–F) Log2 ratios of intracellular vs. extracellular |G*(ω)| for MCF10-CA1 cells (D), MCF7 cells (E), and D2.A1 cells (F) embedded in 3D HA treated with blebbistatin. (J–L) Log2 ratios of blebbistatin-treated vs. untreated control |G*(ω)| for MCF10-CA1 cells (J), MCF7 cells (K), and D2.A1 cells (L) embedded in 3D HA. P values from 2-way ANOVA are shown above or below each bar in A–F (**P < 0.01 and ***P < 0.001).