Table 2.
Prevalence of single nucleotide polymorphisms (SNPs) in T-ACTIN1 in infertile or proven fertile populations
| Position | Genotype | Number (%) of SNP | Reference | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Nucleotide* | Amino acid | Infertile (%) | Proven fertile (%) | (NCBI dbSNP rs#) | ||||||
| T-ACTIN1/ACTL7B | 48 | 16 | D | C/C | 161 (57.1) | 54 (60.7) | rs3750468 | |||
| C/T | 102 (36.2) | 28 (31.5) | ||||||||
| T/T | 19 (6.7) | 7 (7.9) | P=0.74 | |||||||
| 561 | 187 | Y | C/C | 161 (57.1) | 54 (60.7) | rs11543179 | ||||
| C/T | 102 (36.2) | 28 (31.5) | ||||||||
| T/T | 19 (6.7) | 7 (7.9) | P=0.74 | |||||||
| 870 | 290 | T | C/C | 218 (77.7) | 66 (74.2) | rs3750467 | ||||
| C/T | 62 (22.0) | 21 (23.6) | ||||||||
| T/T | 2 (0.7) | 2 (2.2) | P=0.23 | |||||||
| 1137 | 379 | S | C/C | 282 (100) | 87 (97.8) | rs769443334 | ||||
| C/T | 0 (0) | 2 (2.2) | ||||||||
| T/T | 0 (0) | 0 (0) | ||||||||
| 1171 | 391 | Q | C/C | 282 (100) | 88 (98.9) | rs750564969 | ||||
| Q/Ter | C/T | 0 (0) | 1 (1.1) | |||||||
| Ter | T/T | 0 (0) | 0 (0) | |||||||
| Total | 282 | 89 | ||||||||
D; Aspartate, Y; Tyrosine, T; Threonine,S; Serine, Q; Glutamine, Ter; Termination, and *; The nucleotide positions relative to the first methionine.