Table 3.
Prevalence of single nucleotide polymorphisms (SNPs) in T-ACTIN1 in infertile or proven fertile populations
| Position | Genotype | Number (%) of SNP | Reference | ||||
|---|---|---|---|---|---|---|---|
| Nucleotide* | Amino acid | Infertile (%) | Proven fertile (%) | (NCBI dbSNP rs#) | |||
| T-ACTIN1/ACTL7B | 118 | 40 | R | C/C | 28 (99.6) | 89 (100) | rs201549336 |
| C/A | 1 (0.4) | 0 (0) | |||||
| A/A | 0 (0) | 0 (0) | |||||
| 133 | 45 | R | C/C | 282 (100) | 88 (98.9) | rs368653764 | |
| R/C | C/T | 0 (0) | 1 (1.1) | ||||
| C | T/T | 0 (0) | 0 (0) | ||||
| 153 | 51 | P | A/A | 218 (99.6) | 89 (100) | In present study | |
| A/ | 1 (0.4) | 0 (0) | |||||
| G/G | 0 (0) | 0 (0) | |||||
| 528 | 176 | P | A/A | 278 (98.6) | 88 (98.9) | rs3739692 | |
| A/T | 4 (4.1) | 1 (1.1) | |||||
| T/T | 0 (0) | 0 (0) | |||||
| 657 | 219 | V | G/G | 261 (92.6) | 82 (92.1) | rs3739693 | |
| G/A | 21 (7.4) | 4 (4.5) | |||||
| AA | 0 (0) | 3 (3.4) | |||||
| 1018 | 340 | V | G/G | 261 (92.6) | 82 (92.1) | rs7872077 | |
| V/M | G/A | 21 (7.4) | 4 (4.5) | ||||
| M | A/A | 0 (0) | 3 (3.4) | ||||
| Total | 282 | 89 | |||||
R; Arginine, C; Cysteine, P; Proline, V; Proline, M; Methionine, and *; The nucleotide positions relative to the first methionine.