Fig. 1.

Sequence and targets of miR-134. a - Mouse miR-134 stem-loop structure containing both mmu-miR-134-3p (blue text) and mmu-miR-134-5p (red text). b - An overview of the biogenesis and selected mRNA targets of miR-134. Among those most likely to be relevant to epilepsy are CREB [37], DCX [38] and Pum2 [26] within the soma and LimK1 [11,14] in dendritic spines. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)