Table 3.
Independent and adjusted ORs of potential factors following logistic regression analysis of GDM
| Univariate logistic regression (n = 4771) | Multivariate logistic regression using Bayesian inference (n = 4771) | ||
|---|---|---|---|
| OR (95% CI) | p value | ORa (95% HDI) | |
| Age, 18~30 years | reference | ||
| 30~35 | 1.83 (1.48, 2.27) | < 0.0001 | 1.38 (1.01, 1.88) |
| 35–40 | 2.53 (1.94, 3.30) | < 0.0001 | 1.69 (1.06, 2.63) |
| 40–45 | 3.72 (2.18, 6.36) | < 0.0001 | 3.03 (1.06, 7.82) |
| Prepregnancy BMI, 16~23 kg/m2 | reference | ||
| 23–27.5 | 1.92 (1.56, 2.36) | < 0.0001 | 1.17 (0.83, 1.59) |
| 27.5–30 | 5.17 (3.53, 7.56) | < 0.0001 | 3.39 (1.92, 5.68) |
| 30~35 | 4.26 (2.63, 6.91) | 3.39 (1.92, 5.68) | 1.96 (0.98, 4.09) |
| 35~45 | 2.64 (1.41, 4.96) | 0.0025 | 0.32 (0.02, 2.70) |
| FPG, 2.0~4.4 mM | reference | ||
| 4.4~5.1 | 2.56 (1.72, 3.81) | < 0.0001 | 2.44 (1.54, 4.33) |
| 5.1~7.0 | 21.16 (13.89, 32.23) | < 0.0001 | 16.58 (9.21, 31.30) |
| TG 0~1.69 mM | reference | ||
| 1.69~2.26 | 1.75 (1.38, 2.21) | 16.58 (9.21, 31.30)16.58 (9.21, 31.30) | 1.40 (0.92, 1.92) |
| 2.26~12.0 | 3.04 (2.31, 4.00) | < 0.0001 | 2.10 (1.45, 3.56) |
| Abnormal gravidity outcome (0 time) | reference | ||
| ≥1 time# | 1.49 (1.25, 1.77) | < 0.0001 | 1.05 (0.75, 1.41) |
| TC, 0~5.2 mM | reference | ||
| 5.2~10 | 1.23 (1.01,1.50) | 0.0381 | 0.88 (0.58, 1.31) |
| HDL, ≥1.0 mM | reference | ||
| < 1.0 | 3.34 (1.17, 9.57) | 0.0246 | 2.67 (0.83, 8.56) |
| LDL, 0~2.6 mM | reference | ||
| 2.6~12 | 1.15 (0.19, 6.89) | 0.361 | 1.15 (0.77, 1.69) |
Note: ORa, adjusted OR; only the lower cut off value was included in each subgroup. CI, confidence interval; HDI, high density interval; #, at least one preterm delivery miscarriage or induced abortion;