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. 2019 Jul 19;38:320. doi: 10.1186/s13046-019-1314-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Identification of candidate proteins associated with 5-FU resistance. a. SDS-PAGE and silver-staining showed the different proteins in Exo/P and Exo/R. b. GO analysis of proteins of Exo/R. Proteins were categorized with the Biological Processes, Molecular functions and Cellular Components. c. Scatterplot showed the alterations in RKO/R and RKO/P. Yellow and blue spots indicated the up-regulated and down-regulated genes. d. Venn diagram indicated the shared and unique genes names among RNA-seq, Proteomics (proteins were converted to their corresponding gene names on Uniprot) and the search results on PubMed