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. 2019 Jul 19;38:320. doi: 10.1186/s13046-019-1314-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Exosomal p-STAT3 derived from RKO/R cells induce 5-FU resistance in RKO/P cells in vivo. a. Flowchart of mice experiment. b. Tumors picture from mice treated with DP (DMSO + Exo/P), DR (DMSO + Exo/R), SP (stattic + Exo/P), SR (stattic + Exo/R). c. Tumor growth curves of mice treated with DP (DMSO + Exo/P), DR (DMSO + Exo/R), SP (stattic + Exo/P), SR (stattic + Exo/R). Treatment started on Day 9 and tumor volumes was measured every 2 days. d. The tumor weights from mice treated with DP (DMSO + Exo/P), DR (DMSO + Exo/R), SP (stattic + Exo/P), SR (stattic + Exo/R). e. The curves of body weights of mice treated with DP (DMSO + Exo/P), DR (DMSO + Exo/R), SP (stattic + Exo/P), SR (stattic + Exo/R). (n = 4, *P < 0.05)