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. 2019 Jul 19;19:715. doi: 10.1186/s12885-019-5927-3

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Profiling cellular composition of HNSCC tumors using scRNA-seq. a 2D t-sne projection of the expression profiles of 5,712 single cells (3,259 immune cells and 2,453 malignant cells) from 20 HNSCC tumors and lymph node samples of 16 patients. Single cells are shown in dot and colored by cell types. b Cell composition per sample. Patients are ordered by their fractions of malignant cells. c The same 2D t-sne projection as (a) with cells colored by patient origins