Skip to main content
. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Curr Opin Virol. 2018 Jul 24;33:42–46. doi: 10.1016/j.coviro.2018.07.002

Figure 1:

Figure 1:

Heterogeneity in viral genomic content of individual infected cells. Variation in both the genomic content of infecting virions and the effective multiplicity of infection result in heterogeneity in the copy numbers of individual viral gene segments (depicted as colored bars) within individual infected cells. Differences in these infected cell genotypes may result in distinct single cell phenotypes in virus production (indicated by the number of grey virions), host transcriptional responses to infection (indicated by the number of interferon (IFN) symbols), and cell fate (indicated by the number of skulls).