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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: J Invest Dermatol. 2018 Dec 10;139(6):1264–1273. doi: 10.1016/j.jid.2018.10.046

Figure 2. A20 robustly and ABIN1 modestly represses IL-17A induced inflammatory transcriptional programs.

Figure 2

Top panel depicts relative expression (log2 fold change) of mock infected (GFP) keratinocytes incubated with IL-17A for 24 hours versus untreated mock infected keratinocytes. Bottom panel depicts relative expression (log2 fold change) for either A20 or ABIN1 overexpressing keratinocytes compared to mock infected (GFP) keratinocytes, all samples treated with IL-17A for 24 hrs. Data shown represents edgeR RNA-seq differential expression results for 6 replicates for each permutation (FDR < 0.05 except for non-shaded bars).