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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: J Invest Dermatol. 2018 Dec 10;139(6):1264–1273. doi: 10.1016/j.jid.2018.10.046

Figure 5. Inflammation predominates the response to A20 and ABIN1 overexpression in the context of cytokine stimulation.

Figure 5

Unsupervised hierarchical clustering dendrogram and heatmap of gene RNA expression values. Each column represents RNA-seq CPM values for one of six replicates (3 replicates each for 2 pooled keratinocyte isolates) for 9 different treatment conditions (GFP expressing (negative control), A20 overexpressing, or ABIN1 overexpressing keratinocytes, with and without 24 hours of IL-17A or TNFα stimulation). Each row represents one of the 861 differentially expressed genes with FDR < 1 ×10-5. The color key represents for each row, deviation from the mean in standard deviations.