Table 5.

Demographic, phenotypic and genotypic features of MBL-producing Pseudomonas aeruginosa

Group	Carbapenem-resistance genes				Sample	Isolate source	Hospital	ESBL production	blaCTXM15	Resistance pattern
blaIMP	blaVIM	blaGIM	blaSPM
A	+	–	+	–	PA1 PA2 PA8	ICU Wound swab ICU	Minia University	–,+_	–,–	CAZ, CN, AK, PB, MEM CAZ, CEP, TGC, MEM CAZ, CN, CT, CIP, IPM
B	+	+	–	+	PA7	Stool	Minia University	_	_	CAZ, CEP, AK, CT, PB, MEM
C	+	–	–	–	PA9	Wound swab	Minia University	+	+	CAZ, CN, TGC, CIP, IPM
D	+	–	–	+	PA11 PA33	Ear discharge Wound swab	Minia University	–,+	–,+	CAZ, CEP, AK, PB, CIP, IPM, CAZ, CEP, CN, CT, MEM
E	+	–	+	+	PA13	ICU	Minia University	+	+	CAZ, CN, AK, TGC, PB, MEM
F	+	+	–	–	PA16	Stool	Minia University	_	_	CAZ, CEP, AK, TGC, CIP, MEM
G	–	+	+	+	PA19	Wound swab	Minia University	_	_	CAZ, CN, AK, CT, PB, IPM
H	–	+	+	–	PA27	Sputum	Chest Hospital	+	_	CAZ, CEP, CN, AK, TGC, PB, MEM

Notes: A, MBL-producing P. aeruginosa isolates positive for bla_IMP and bla_GIM; B, MBL-producing P. aeruginosa isolates positive for bla_IMP, bla_VIM, and bla_SPM; C, MBL- producing P. aeruginosa isolates positive for bla_IMP; D, MBL-producing P. aeruginosa isolates positive for bla_IMPand bla_SPM; E, MBL-producing P. aeruginosa isolates positive for bla_IMP, bla_GIM, and bla_SPM; F, MBL-producing P. aeruginosa isolates positive for bla_IMP and bla_VIM; G, MBL-producing P. aeruginosa isolates positive for bla_VIM, bla_GIM, and bla_SPM; H, MB-producing P. aeruginosa isolates positive for bla_VIM and bla_GIM.

Abbreviations: ESBL, extended-spectrum β-lactamase; MBL, metallo-β-lactamase; ICU, intensive-care unit; CAZ, Ceftazibime, CN, Gentamicin, AK, Amikacin, PB, ploymxin B, MEM, meropenem, TGC, Tigecycline , CEP, cefeperazone, CT, colistin, CIP, ciprofloxacin, IPM, imipenem; IMP, imipenemase; VIM, Verona integron–encoded MBL; GIM, German imipenemase MBL; SPM, S>o Paulo MBL.