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. 2019 Jul 16;11:6603–6614. doi: 10.2147/CMAR.S204346

Table 16.

The assessment of patients’ survival depending on sex, age, stage of disease, diagnostic procedures and treatment

Variable Survival rate (months) P-value
<12
N=104
12–24
N=46
>24
N=83
Gender: 0.034
 Female 17 (16.3%) 12 (26.1%) 27 (32.5%)
 Male 87 (83.7%) 34 (73.9%) 56 (67.5%)
Age (years): 0.036
 <50 11 (10.6%) 5 (10.9%) 15 (18.1%)
 50–60 40 (38.5%) 16 (34.8%) 26 (31.3%)
 60–70 34 (32.7%) 24 (52.2%) 34 (41.0%)
 >70 19 (18.3%) 1 (2.1%) 8 (9.6%)
Degree of spread to regional <0.001
 N1 10 (9.6%) 9 (19.6%) 14 (16.9%)
 N2 23 (22.1%) 25 (54.4%) 52 (62.6%)
 N3 71 (68.3%) 12 (26.1%) 17 (20.5%)
Panendoscopy revealed primary tumor n=23 n=31 n=51 0.802
 Yes 7 (30.4%) 12 (38.7%) 17 (33.3%)
 No 16 (69.6%) 19 (61.3%) 34 (66.7%)
PET - revealed primary tumor n=21 n=16 n=33 0.757
 Yes 8 (38.1%) 8 (50.0%) 15 (45.5%)
 No 13 (61.9%) 8 (50.0%) 18 (54.5%)
Cervical lymph node groups:
 I 7 (6.7%) 1 (2.2%) 1 (1.2%) 0.120
 II 91 (87.5%) 39 (84.8%) 75 (90.4%) 0.634
 III 70 (67.3%) 28 (60.9%) 46 (55.4%) 0.249
 IV 41 (39.4%) 7 (15.2%) 11 (13.3%) <0.001
 V 23 (22.1%) 3 (6.5%) 5 (6.0%) 0.002
 VI 2 (1.9%) 0 (0.0%) 0 (0.0%) 0.286
Tonsillectomy 4 (3.8%) 14 (30.4%) 19 (22.9%) <0.001
Pathologic type: 0.090
 1 - squamous cell carcinoma 90 (86.5%) 38 (82.6%) 74 (89.2%)
 2 – adenocarcinoma 2 (1.9%) 3 (6.5%) 3 (3.6%)
 3 – melanoma 1 (1.0%) 4 (8.7%) 3 (3.6%)
 4 – lymphoma 0 (0.0%) 1 (2.2%) 0 (0.0)
 5 – other 11 (10.6%) 0 (0.0%) 3 (3.6%)
Surgery 34 (32.7%) 24 (52.2%) 51 (61.4%) <0.001
Radiotherapy 53 (51.0%) 40 (87.0%) 73 (88.0%) <0.001
Chemotherapy 50 (48.1%) 30 (65.2%) 55 (66.3%) 0.023
ECOG performance status: <0.001
 0 19 (18.3%) 25 (54.3%) 59 (71.1%)
 1 55 (52.9%) 20 (43.5%) 21 (25.3%)
 2 23 (22.1%) 1 (2.2%) 2 (2.4%)
 3 6 (5.8%) 0 (0.0%) 1 (1.2%)
 4 1 (1.0%) 0 (0.0%) 0 (0.0%)
Treatment: <0.001
 Radical 23 (22.1%) 35 (76.1%) 77 (92.8%)
 Palliative 81 (77.9%) 11 (23.9%) 6 (7.2%)

Note: Bold values represent statistically significant.

Abbreviations: ECOG, Eastern Cooperative Oncology Group.