Table 16.
Variable | Survival rate (months) | P-value | ||
---|---|---|---|---|
<12 N=104 |
12–24 N=46 |
>24 N=83 |
||
Gender: | 0.034 | |||
Female | 17 (16.3%) | 12 (26.1%) | 27 (32.5%) | |
Male | 87 (83.7%) | 34 (73.9%) | 56 (67.5%) | |
Age (years): | 0.036 | |||
<50 | 11 (10.6%) | 5 (10.9%) | 15 (18.1%) | |
50–60 | 40 (38.5%) | 16 (34.8%) | 26 (31.3%) | |
60–70 | 34 (32.7%) | 24 (52.2%) | 34 (41.0%) | |
>70 | 19 (18.3%) | 1 (2.1%) | 8 (9.6%) | |
Degree of spread to regional | <0.001 | |||
N1 | 10 (9.6%) | 9 (19.6%) | 14 (16.9%) | |
N2 | 23 (22.1%) | 25 (54.4%) | 52 (62.6%) | |
N3 | 71 (68.3%) | 12 (26.1%) | 17 (20.5%) | |
Panendoscopy revealed primary tumor | n=23 | n=31 | n=51 | 0.802 |
Yes | 7 (30.4%) | 12 (38.7%) | 17 (33.3%) | |
No | 16 (69.6%) | 19 (61.3%) | 34 (66.7%) | |
PET - revealed primary tumor | n=21 | n=16 | n=33 | 0.757 |
Yes | 8 (38.1%) | 8 (50.0%) | 15 (45.5%) | |
No | 13 (61.9%) | 8 (50.0%) | 18 (54.5%) | |
Cervical lymph node groups: | ||||
I | 7 (6.7%) | 1 (2.2%) | 1 (1.2%) | 0.120 |
II | 91 (87.5%) | 39 (84.8%) | 75 (90.4%) | 0.634 |
III | 70 (67.3%) | 28 (60.9%) | 46 (55.4%) | 0.249 |
IV | 41 (39.4%) | 7 (15.2%) | 11 (13.3%) | <0.001 |
V | 23 (22.1%) | 3 (6.5%) | 5 (6.0%) | 0.002 |
VI | 2 (1.9%) | 0 (0.0%) | 0 (0.0%) | 0.286 |
Tonsillectomy | 4 (3.8%) | 14 (30.4%) | 19 (22.9%) | <0.001 |
Pathologic type: | 0.090 | |||
1 - squamous cell carcinoma | 90 (86.5%) | 38 (82.6%) | 74 (89.2%) | |
2 – adenocarcinoma | 2 (1.9%) | 3 (6.5%) | 3 (3.6%) | |
3 – melanoma | 1 (1.0%) | 4 (8.7%) | 3 (3.6%) | |
4 – lymphoma | 0 (0.0%) | 1 (2.2%) | 0 (0.0) | |
5 – other | 11 (10.6%) | 0 (0.0%) | 3 (3.6%) | |
Surgery | 34 (32.7%) | 24 (52.2%) | 51 (61.4%) | <0.001 |
Radiotherapy | 53 (51.0%) | 40 (87.0%) | 73 (88.0%) | <0.001 |
Chemotherapy | 50 (48.1%) | 30 (65.2%) | 55 (66.3%) | 0.023 |
ECOG performance status: | <0.001 | |||
0 | 19 (18.3%) | 25 (54.3%) | 59 (71.1%) | |
1 | 55 (52.9%) | 20 (43.5%) | 21 (25.3%) | |
2 | 23 (22.1%) | 1 (2.2%) | 2 (2.4%) | |
3 | 6 (5.8%) | 0 (0.0%) | 1 (1.2%) | |
4 | 1 (1.0%) | 0 (0.0%) | 0 (0.0%) | |
Treatment: | <0.001 | |||
Radical | 23 (22.1%) | 35 (76.1%) | 77 (92.8%) | |
Palliative | 81 (77.9%) | 11 (23.9%) | 6 (7.2%) |
Note: Bold values represent statistically significant.
Abbreviations: ECOG, Eastern Cooperative Oncology Group.