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. 2019 Jul 12;25:5170–5180. doi: 10.12659/MSM.916815

Figure 4.

Figure 4

MiR-31-3p negatively regulated RASA2 by directly bind to it. (A) The predicted consequential pairing of target region of RASA2 and miR-31-3p, and the schematic diagram of establishment of luciferase recombinant plasmid. (B, C) Dual-luciferase reporter assay was performed in 2 human MTC cell lines MZ-CRC-1 and TT to verify the interaction between miR-31-3p and RASA2. (D, E) Relative RASA2 mRNA and protein expression in TT and MZ-CRC-1 cells treated with miR-31-3p mimic or control.