Table 2.
Risk factors for CMB development | ||||
---|---|---|---|---|
Univariate Poisson Analysis |
Multivariate Poisson Analysisa | |||
Characteristic | Incidence Rate Ratio |
P-value | Incidence Rate Ratio | P-value |
Time since RT, each additional year | 1.05 (1.02, 1.09) | <.001 | 1.10 (1.04, 1.16) | <.001 |
>1 surgical resection | 1.98 (1.12, 3.51) | .022 | 2.42 (1.36, 4.30) | .004 |
Tumor pathology | ||||
Glioblastoma vs anaplastic astrocytoma | 2.69 (1.29, 5.61) | .010 | 2.41 (1.21, 4.77) | .014 |
Glioblastoma vs other | 1.25 (.464, 3.37) | .661 | .257 (.064, 1.04) | .060 |
Tumor location | ||||
Frontal vs temporal | .454 (.188, 1.10) | .083 | .445 (.213, .932) | .035 |
Frontal vs parietal | .353 (.066, 1.87) | .225 | .204 (.046, .900) | .039 |
Frontal vs occipital, cerebellum or brainstem | 1.11 (.413, 2.97) | .840 | 3.58 (1.20, 10.6) | .025 |
Maximum brain radiation, each additional Gyb | 1.00 (.999,1.00) | .579 | not included as significant | |
Type of SWI acquired | ||||
Multi-echo vs single-echo SWIc | .534 (.291, .980) | .046 | .717 (.425, 1.21) | .217 |
race, sex, and age at time of RT included as covariates.
37 subjects
difference in slice thickness: 1mm for single echo SWI and 2mm for multi-echo SWI.