Table 2.
Neonatal outcomes of singleton live births in fresh ET and FET cycles
| Fresh cycles | Frozen cycles | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Study group N = 1196 |
Control group N = 1576 |
P value | OR, 95% CI | Adjusted P value |
Adjusted OR, 95% CI |
Study group N = 1275 |
Control group N = 2173 |
P value | OR, 95% CI | Adjusted P value |
Adjusted OR, 95% CI |
|
| Gestational age | 262.8 ± 8.4 | 268.9 ± 13.9 | 0.000 | / | / | / | 263.0 ± 15.7 | 273.0 ± 10.5 | 0.000 | / | / | / |
| PTB | 258 (21.6) | 159 (10.1) | 0.000 | 2.45(1.98–3.03) | 0.000* | 2.41(1.93–2.99) | 230 (18.0) | 160 (7.4) | 0.000 | 2.77 (2.23,3.43) | 0.000* | 2.68 (2.15,3.33) |
| birthweight | 2962.4 ± 563.1 | 3104.9 ± 498.5 | 0.000 | / | / | / | 3099 ± 662.1 | 3352 ± 671.5 | 0.000 | / | / | / |
| LBW | 201(16.8) | 138 (8.8) | 0.000 | 2.11 (1.67–2.65) | 0.000* | 2.21 (1.74–2.80) | 204 (16.0) | 145 (6.6) | 0.000 | 2.67 (2.13–3.34) | 0.000* | 2.07 (2.12,3.35) |
| SGA | 90 (7.5) | 111 (7.1) | 0.561 | 1.09 (0.82–1.45) | 0.960 | 1.01 (0.75,1.35) | 60 (4.7) | 104 (4.8) | 0.915 | 0.98 (0.71–1.36) | 0.730 | 0.94 (0.68,1.31) |
| Congenital malformation | 20 (1.7) | 28 (1.8) | 0.835 | 0.94 (0.53–1.68) | 0.640 | 0.87 (0.48–1.57) | 25 (2.0) | 43 (19.8) | 0.971 | 0.99 (0.60,1.63) | 0.940 | 0.98 (0.59,1.62) |
| Pediatrics admission | 280 (23.4) | 169 (10.7) | 0.000 | 2.55 (2.07–3.13) | 0.000* | 2.62 (2.12–3.24) | 256 (20.1) | 190 (8.7) | 0.000 | 2.62 (2.14–3.21) | 0.000* | 2.60 (2.12,3.19) |
| NICU admission | 60 (5.0) | 26 (1.6) | 0.001 | 1.98 (1.32,2.96) | 0.001* | 2.04 (1.36,3.08) | 46 (3.6) | 36 (1.7) | 0.000 | 2.22 (1.43,3.46) | 0.001* | 2.21 (1.41,3.44) |
*p < 0.05 was statistically significant. Adjusted for confounders, including age of women, BMI, value of AMH, infertile years, current cycle, AFC, cause of infertility, number of oocytes retrieved, endometrial thickness at the day of transplantation, number of high-quality embryos, embryo stage