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. 2019 Jul 7;2019:1893047. doi: 10.1155/2019/1893047

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Copyright © 2019 Sergiy V. Kushchayev et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Imaging in MEN syndrome. 18F-FDG PET/CT (a) and 18F-FDOPA PET/CT (b) in MEN2B syndrome with metastatic pheochromocytoma (fractionated norepinephrine: 994 pg/ml, normal: 18-112 pg/ml; fractionated metanephrine: 1099 pg/ml, normal: 12-61 pg/ml) and metastatic medullary carcinoma (calcitonin: 5575, normal: < 8 pg/ml). In this case, the primary pheochromocytoma is seen in all images (yellow arrow); however, metastatic lesions are best visualized on 18F-FDOPA PET/CT (red arrows). Imaging cannot differentiate between medullary carcinoma metastases and metastases originating from pheochromocytoma.