Table 1:

Organ weights determined in WT and Cyp2b9/10/13-null mice after 10-weeks of dietary treatment in male (A) and female (B) mice.

A
Mouse model	Body weight	WAT	Liver	Kidney	Brain
WT-NDM	26.48±0.57	0.51±0.06	1.23±0.03	0.34±0.01	0.48±0.03
WT-HFD M	30.43±0.92b**	1.96±0.22b***	1.06±0.04b*	0.37±0.01	0.44±0.00
Cyp2b-null ND M	25.75±0.39	0.69±0.06	1.08±0.03a*	0.31±0.01	0.46±0.01
Cyp2b-null HFD M	34.12±0.88c***d*	3.04±0.19c***d***	1.08±0.04	0.37±0.02c**	0.43±0.01
B
Mouse model	Body weight	WAT	Liver	Kidney	Brain
WT-NDF	20.47±0.44	0.36±0.06	0.87±0.03	0.26±0.01	0.44±0.00
WT-HFD F	23.17±0.87b*	0.95±0.15b*	0.84±0.03	0.26±0.01	0.45±0.00
Cyp2b-null ND F	20.29±0.22	0.33±0.03	0.83±0.02	0.25±0.01	0.45±0.00
Cyp2b-null HFD F	24.15±0.93c**	1.22±0.24c**	0.87±0.04	0.28±0.01c	0.45±0.01

Data represented as mean (g) +/− SEM (n = 8/9). Statistical significance determined by one-way ANOVA followed by Fisher’s LSD as the post-hoc test.

^‘a’indicates WT ND different than Cyp2b9/10/13-null ND

^‘b’indicates WT ND different than WT HFD

^‘c’indicates Cyp2b9/10/13-null ND different than Cyp2b9/10/13-null HFD

^‘d’indicates WT HFD different than Cyp2b9/10/13-null HFD,

No asterisk indicates a p-value ≤ 0.05,

^*indicates a p-value ≤ 0.01,

^**indicates a p-value ≤ 0.0001 and

^***indicates a p-value ≤ 0.00001.