Table 5:

Comparison of the number of up- and down-regulated genes in female mice within specific KEGG pathways.

KEGG Pathway	Cyp2b-null ND vs WT ND	WT HFD vs WT ND	Cyp2b-null HFD vs WT HFD
PI3K-Akt signaling	5	0	0
Protein processing in endoplasmic reticulum	4	0	6
Insulin resistance/signaling	4	0	0
Apoptosis	4	0	0
FoxO signaling	3	0	0
Circadian rhythm	3	0	0
Cholesterol metabolism	3	1	0
MAPK signaling	3	0	1
Sphingolipid metabolism	2	0	0
Glycerophospholipid metabolism	2	0	0
Retinol metabolism	2	0	1
Calcium signaling	1	0	2
Drug metabolism	1	1	0
NAFLD	1	0	0
Total Perturbations	190	13	49