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. 2019 Jun 19;52(3):45–58. doi: 10.1267/ahc.19006

Table 1. .

Positive ratio of cleaved caspase-3 or Ki67

CTR (n = 4) IRD (n = 4) IRD+Pilo (n = 4)
Cleaved caspase-3
 Parotid gland 0.14 ± 0.13 3.38 ± 1.97 a 1.38 ± 0.56
 Submandibular gland 0.16 ± 0.12 1.62 ± 0.58 b 1.14 ± 0.81
Ki67
 Parotid gland 9.42 ± 9.26 36.2 ± 2.88 c 33.4 ± 10.9
 Submandibular gland 5.65 ± 1.59 16.7 ± 7.78 8.20 ± 1.42

Ratio of positive acinar cells to total acinar cells was calculated as described in the materials and methods section.

Values (%) are mean ± SD.

Two-tailed unpaired t-test was used to compare IRD with CTR and IRD+Pilo with IRD.

a P = 0.04 compared with CTR.

b P = 0.01 compared with CTR.

c P = 0.002 compared with CTR.