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. 2019 Jun 7;16(7):931–938. doi: 10.7150/ijms.32413

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High-resolution respirometry in skin fibroblasts from patients. A, General trace of OCR measurement under basal conditions followed by the sequential addition of oligomycin, FCCP and rotenone plus antimycin A, as indicated. B, Basal OCR in pmol/(s*ml). C-F, ATP-linked, maximal, spare capacity and proton leak-linked OCR as a percentage of basal OCR. Healthy control is #1 and patients #2 to #6. The asterisk indicates the ratios which significantly differ (p < 0.05) between the control patient and fibroblast cultures from patients with mitochondrial cytopathy. Mean +/- SD.