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HP deactivates ERα-36-mediated AKT/GSK3β/β-catenin signaling pathway in TNBC cells HP treatment reduced the p-AKT and downregulated the expression of p-β-catenin and cyclin D1, the downstream genes of ERα-36 signaling, in Mb436 Mock cells (Figure 4A) and Hs578T/ov36 cells (Figure 4B), but not in Mb436/sh36 and Hs578T cells. Data are presented as means ± SD (n= 3). (**, P<0.01 and NS, no significance).
