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. 2019 Jun 10;15(8):1733–1742. doi: 10.7150/ijbs.35138

Figure 3.

Figure 3

Compound 870 is more effective than JQ-1 in terms of its ability to inhibit KLF5 expression and BLBC growth. A. The structures of compound 870 and JQ-1. B. Compound 870 and JQ-1 decreased the cell viability of BLBC cells, as measured by the SRB assay. HCC1806 and HCC1937 cells were treated with the indicated compound 870 and JQ-1 for 72 h. The error bars represent the SD of experimental triplicates. C. Compound 870 and JQ-1 regulate KLF5 and its target gene expression in BLBC cells. HCC1806 and HCC1937 cells were exposed to the indicated compound 870 and JQ-1 for 24 h. The protein levels were detected by immunoblotting. c-MYC was used as a positive control.