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. Author manuscript; available in PMC: 2019 Jul 22.
Published in final edited form as: Lab Invest. 2010 Jun 7;90(10):1457–1467. doi: 10.1038/labinvest.2010.107

Table 2.

Bile acid profile in bile of chow-fed wild-type and intestine-selective FXR knockout mice

Chow diet
WT iFXR-KO
Total biliary bile salts (mM) 27.55 ± 3.80 29.58 ± 7.22
Bile salt species (%)
 Chenodeoxycholate 0.93 ± 0.36 1.02 ± 0.51
 Cholate 47.10 ± 8.14 62.70 ± 7.05#
 Deoxycholate 1.96 ± 1.11 3.32 ± 0.73#
 Hyodeoxycholate 0.75 ± 0.11 0.83 ± 0.14
 α-Muricholate 3.46 ± 0.64 3.13 ± 1.39
 β-Muricholate 41.94 ± 9.13 26.15 ± 6.13#
 ω-Muricholate 2.02 ± 0.26 1.06 ± 0.23#
 Ursodeoxycholate 1.84 ± 0.23 1.78 ± 0.31
Hydrophobicity index −0.352 ± 0.073 −0.217 ± 0.054#

Groups are composed of six chow-fed male mice and samples were taken around 1300 hours. Values are expressed as means ± s.d.

#

P < 0.05 vs control.