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Conservation of potentially druggable cavities of a few examples from the Disprot-pdb dataset.33 (a) Average common atom percentage and rmsd for cyclin-dependent kinase inhibitor 2A (PDB ID: 1HN3), methylosome subunit pICln (PDB ID: 1ZYI), and the protein AF9 chimera (PDB ID: 2LM0). (b–d) Aligned potentially druggable cavities in 1HN3 (b), 1ZYI (c), and 2LM0 (d).
