Figure 1.

Developmental phenotypes of cybrid strains (A) Egg-to-adult development times of flies of the indicated sex and genotype. Note that the mtKSA2 haplotype was pupal lethal in the ntko^25t background. (B) Late pupal mtDNA copy number, arbitrarily normalized to that of a wild-type ORT adult strain. All data plotted as means ± SD from at least four replicate vials. Asterisks (*, **, ***) denote statistically significant differences between nuclear backgrounds, for flies of a given sex and mtDNA haplotype (Student’s t-test, P < 0.05, 0.01, 0.001, respectively).