Table 6.

Most parsimonious model of clinical and microbiological factors associated with clustering in non-Asian patients

	Clustering*		Unadjusted		Adjusted
	Yes (n = 12)	No (n = 56)
	n (%)	n (%)	OR (95%CI)	P value	OR (95%CI)	P value
Age ≥65 years†	0	2 (3.7)	Could not calculate
Hispanic †	12 (100)	42 (75.0)	Could not calculate
Diabetes mellitus†	3 (25.0)	1 (1.8)	17.1 (1.23–978.90)	0.031	10.0 (0.53–751.00)	0.169
BCG vaccination†	1 (8.3)	10 (17.9)	0.42 (0.01–3.59)	0.751
Injecting drug user in last 12 months†	1 (8.3)	1 (1.8)	4.74 (0.06–392.20)	0.656
Excessive alcohol in last 12 months†	9 (75.0)	12 (22.2)	10.0 (2.09–66.80)	0.001	7.78 (1.55–52.50)	0.009
East-Asian lineage†	4 (33.3)	7 (12.5)	3.42 (0.60–17.70)	0.188
With S531L mutation†	6 (50.0)	36 (65.5)	0.53 (0.12–2.29)	0.495
With katG mutation†	8 (66.7)	40 (72.7)	0.75 (0.17–3.93)	0.918

^*Defined as isolates collected in the same state and sharing identical spoligotyping, 24-locus mycobacterial interspersed repetitive units typing, insertion sequence 6110 restriction fragment length polymorphism pattern and drug-resistance-associated mutations.

^†As expected cell counts were <5, unadjusted ORs and P values were calculated using the exact logistic method.

OR = odds ratio; CI = confidence interval; BCG = bacille Calmette-Guérin.