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. Author manuscript; available in PMC: 2019 Jul 22.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2016 Jan 22;95(2):782–790. doi: 10.1016/j.ijrobp.2016.01.028

Figure 4. — Effect of AZD1775 on cell cycle progression. A, Flow cytometry using anti-phospho-histone H3 antibody was performed to determine the effect of AZD1775 on cell cycle progression from G2 to mitosis. B, In the Hep3B and Huh7 cell lines treatment with AZD1775 and radiation resulted in increased pHH3 staining. This effect was not seen in the HepG2 cell line, likely related to the ability of these cells to arrest in G1.

Figure 4. — Effect of AZD1775 on cell cycle progression. A, Flow cytometry using anti-phospho-histone H3 antibody was performed to determine the effect of AZD1775 on cell cycle progression from G2 to mitosis. B, In the Hep3B and Huh7 cell lines treatment with AZD1775 and radiation resulted in increased pHH3 staining. This effect was not seen in the HepG2 cell line, likely related to the ability of these cells to arrest in G1.