Table 3.
Logistic regression analyses for association between hypertension and prolonged QTc interval.
| Group | Prolonged QTc | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|---|
| n (%) | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Total | |||||||
| Normotension | 389 (7.5) | 1 | 1 | 1 | |||
| Hypertension | 982 (18.4) | 2.48 (2.17–2.82) | < 0.001 | 1.79 (1.55–2.07) | < 0.001 | 1.71 (1.48–1.98) | < 0.001 |
| Male | |||||||
| Normotension | 120 (5.4) | 1 | 1 | 1 | |||
| Hypertension | 416 (16.3) | 2.99 (2.40–3.72) | < 0.001 | 2.14 (1.69–2.72) | < 0.001 | 2.03 (1.60–2.59) | < 0.001 |
| Female | |||||||
| Normotension | 269 (9.0) | 1 | 1 | 1 | |||
| Hypertension | 566 (20.3) | 2.23 (1.89–2.63) | < 0.001 | 1.63 (1.36–1.95) | < 0.001 | 1.56 (1.30–1.88) | < 0.001 |
Abbreviations. CI: confidence interval; OR: odds ratio; QTc: QT interval corrected for heart rate with Bazett's formula.
Note. Model 1: adjusted for age, gender, and race; Model 2: additional adjustments for BMI, FBG, TC, TG, LDL-C, HDL-C, SUA, current smoking, drinking status, serum calcium, potassium and magnesium, heart rate, history of heart disease, and any medication used; Model 3: additional adjustments for LVH.