Scheme 3. Indole Synthesis via Sonogashira Coupling with 2-Bromoanilines,
Reaction conditions: 1. 8 (0.5 mmol), 9 (0.63 mmol), P2 (5.0 mol %), TMP (1.0 mmol), ACN (2.0 mL), rt under argon atmosphere. 2. HCl (2.5 mmol), 90 °C.
Isolated yield.
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