Table 1. Inhibition of H460 Proliferation.
| H460 |
|||
|---|---|---|---|
| IC50a (μM) |
|||
| compound | AIR | N2 | AIR/N2 |
| GLU-IMI-PTX | 0.409 ± 0.031 | 0.183 ± 0.029 | 2.2 |
| AZO-IMI-PTX | 0.163 ± 0.029 | 0.086 ± 0.009 | 1.9 |
| IMI-PTX | 0.094 ± 0.012 | 0.043 ± 0.010 | 2.2 |
| PTX | 0.007 ± 0.001 | 0.009 ± 0.002 | 0.8 |
Data presented are the mean ± SD value of three independent determinations.