Stewart 1998.
Methods | Randomised controlled trial No information provided about duration of study |
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Participants | 80 participants (40 in each group) Elective intraperitoneal colorectal resections without stoma formation (Ileocolic resection (10); hemicolectomy (right or left) (35); subtotal colectomy (11); anterior resection (24)) Route of feeding: oral Mean age (range): 58 (25‐89) (intervention group), 59 (17‐88) (control group) Sex ratio (M:F): 19/21 (intervention group), 18/22 (control group) |
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Interventions | Intervention group: allowed free fluids from 4 hours after operation and progressed to a solid diet from the first POD at their own discretion. Control group: remained fasting until passage of flatus or bowel motion, and were then commenced on clear fluids and progressed to a solid diet over 24 to 48 hours at the surgeon’s discretion. |
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Outcomes | Wound infection, anastomotic leakage, mortality, pneumonia, LoS, vomiting. | |
Notes | Country of study: Australia | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Patients randomly assigned according to a computer number generator to one of two groups. |
Allocation concealment (selection bias) | Unclear risk | No information provided. |
Blinding of participants (performance bias) All outcomes | High risk | No reports of attempts to blind participants. Participants are unlikely to be adequately blinded with an intervention of this nature. |
Blinding of personnel (performance bias) All outcomes | High risk | No reports of attempts to blind personnel. Participants are unlikely to be adequately blinded with an intervention of this nature. |
Blinding of outcome assessor (detection bias) ‐ wound infections | High risk | Assessors were not blinded. |
Blinding of outcome assessor (detection bias) ‐ intraabdominal abscesses | Unclear risk | NA ‐ not assessed. |
Blinding of outcome assessor (detection bias) ‐ postoperative complications e.g. acute myocardial infarction, thrombosis or pneumonia | High risk | (Respiratory complications, cardiovascular complications, urinary tract infection, pneumonia) Assessors were not blinded. |
Blinding of outcome assessor (detection bias) ‐ anastomotic leakage/dehiscence | High risk | Assessors were not blinded. |
Blinding of outcome assessor (detection bias) ‐ mortality | Low risk | Asessors were not blinded. Outcome assessor unlikely to affect this outcome. |
Blinding of outcome assessor (detection bias) ‐ adverse events (e.g. nausea, vomiting, abdominal distention, aspiration, tube blockage and any other adverse events | High risk | (Vomiting). Assessors were not blinded. |
Blinding of outcome assessor (detection bias) ‐ length of hospital stay | High risk | Asessors were not blinded. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Less than 10% missing data. |
Selective reporting (reporting bias) | Unclear risk | No protocol available. All outcomes listed in methods were reported in the results. |