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. 2019 Jul 18;11:6703–6717. doi: 10.2147/CMAR.S203317

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© 2019 Hsiao et al.

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Changes in electron-transport chain complex enzymatic activity in mononuclear cells in patients with radiation therapy (N=33).

Notes: CII was measured as TTFA-sensitive DCPIP reductase; total complex II determined with coenzyme Q₁ added (CII+Q₁); CIII, measured as antimycin A-sensitive decylubiquinol cytochrome c reductase; CS is mitochondrial marker; SDH was used to measure the first 2 subunits of complex II and served as a membrane-bonded mitochondrial marker enzyme; LDH as a cytoplasm marker. *P<0.05.

Abbreviations: NADH, nicotinamide adenine dinucleotide; NCR, rotenone-sensitive NADH cytochrome c reductase; SCR, antimycin A-sensitive succinate cytochrome c reductase; CII, complex II activity; TTFA, thenoyltrifluoroacetone; DCPIP, dichlorophenol-indophenol; CII+Q1, complex II with coenzyme Q₁; CIII, complex III activity, measured as antimycin A-sensitive decylubiquinol cytochrome c reductase; CIV, complex IV (cytochrome c oxidase) activity; CS, citrate synthase, mitochondrial marker; SDH, succinate dehydrogenase; LDH, lactate dehydrogenase.