Table 4.
Univariate Logistic Regression of State‐Anxiety, Trait‐Anxiety, and Depression for 18‐Month Outcomes in Patients With HFrEF Versus Those With HFpEF
| Variable | Patients With HFrEF | Patients With HFpEF | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P Value | OR | 95% CI | P Value | |
| All‐cause mortality | ||||||
| State‐Anxiety | 1.020 | 0.974–1.068 | 0.396 | 1.073 | 1.013–1.137 | 0.016 |
| Trait‐Anxiety | 0.991 | 0.945–1.039 | 0.711 | 1.081 | 1.007–1.161 | 0.032 |
| Depression | 1.014 | 0.957–1.075 | 0.640 | 1.025 | 0.923–1.138 | 0.649 |
| All‐cause readmission or death | ||||||
| State‐Anxiety | 1.022 | 0.989–1.059 | 0.235 | 1.060 | 1.014–1.109 | 0.011 |
| Trait‐Anxiety | 1.013 | 0.978–1.050 | 0.464 | 1.068 | 1.011–1.128 | 0.019 |
| Depression | 1.023 | 0.974–1.075 | 0.358 | 1.015 | 0.936–1.101 | 0.715 |
| Cardiac readmission or death | ||||||
| State‐Anxiety | 1.017 | 0.981–1.053 | 0.366 | 1.030 | 0.987–1.076 | 0.174 |
| Trait‐Anxiety | 1.021 | 0.985–1.058 | 0.252 | 1.054 | 0.998–1.113 | 0.059 |
| Depression | 1.021 | 0.974–1.070 | 0.394 | 0.974 | 0.889–1.069 | 0.583 |
The interaction effect of the Trait‐Anxiety×group was significant in all‐cause mortality (P=0.046), as well as nonsignificant in all‐cause readmission or death (P=0.115) and cardiac readmission or death (P=0.339). The interaction effect of the State‐Anxiety×group was not significant in all‐cause mortality (P=0.175), all‐cause readmission or death (P=0.210), and cardiac readmission or death (P=0.634). We were unable to conduct the univariate/multiple logistic regression analysis of cardiac mortality because relative competing risks were not considered. Data are given for each 1‐unit increase in continuous variables for State‐Anxiety, Trait‐Anxiety, and Depression. HFpEF indicates heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction; OR, odds ratio.