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Signals involved in NLRP3 inflammasome activation in atherosclerosis. The activation of the NLRP3 inflammasome drives the initiation and progression of atherosclerosis. Shown are the key stimuli identified to date that induce priming and activating of the NLRP3 inflammasome in the atherosclerotic milieu. LDL indicates low‐density lipoprotein; Tet2, tet methylcytosine dioxygenase 2.
