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. Author manuscript; available in PMC: 2019 Jul 22.
Published in final edited form as: Annu Rev Biophys. 2019 Mar 11;48:275–296. doi: 10.1146/annurev-biophys-052118-115325

Figure 1.

Figure 1

Left: A spherical solute of radius A. Two point charges qi and qj are placed at distances ri and rj respectively from the sphere center. Right: Representation of a molecule as a set of overlapping spheres. The integral needed in Eq. 12 can be approximately written as a sum over all of the spheres except for the white one.