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. 2019 Jul 17;12:5751–5765. doi: 10.2147/OTT.S208924

Figure 5.

Figure 5

Oridonin overcomes PANC-1/Gem cell gemcitabine resistance in vivo. (A) Tumor progression timeline with experimental treatment time points. (B) Normal pancreatic tissues and transplantation of PANC-1/Gem cell tumor stained with hematoxylin and eosin. (C) Representative images of tumors formed in nude mice. (D) Statistical comparisons of tumor volumes were measured on the indicated days. Data were expressed as the mean ± standard deviation. *P<0.05 and **P<0.01. (E) Weight of the transplanted tumor. *P<0.05 and **P<0.01. (F) Xenografts from mice were immunochemically stained using GST pi antibodies.

Abbreviation: GST, glutathione S-transferase.