The effects of salt loading and brain-derived neurotrophic factor (BDNF) knockdown in the supraoptic nucleus (SON). A, Daily average fluid intake. B, Daily average urine excretion. C, Daily average food intake. A-C, *P < 0.05 vs euhydrated (Eu) groups and vs baseline. D, Average daily changes in body weight. Data are the mean ± SEM. *P < 0.05 vs Eu groups. Groups: euhydrated rats injected with scrambled (SCR) virus (Eu SCR, n = 8); euhydrated rats injected with shBDNF virus (Eu shBDNF, n = 8); salt loaded rats injected with SCR virus (Salt SCR, n = 8) and salt loaded rats injected with shBDNF virus (Salt shBDNF, n = 8)