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. 2019 Jul;60(8):3119–3126. doi: 10.1167/iovs.19-27321

Table 3.

Pathways Altered in PDR Patients Compared With NPDR Patients

Pathway
 Overlapping Features
 Pathway Size
 P Value
Saturated fatty acids β-oxidation 3 6 0.032
Fatty acid metabolism 4 10 0.038
Vitamin D3 metabolism 3 7 0.048

Pathway analysis was performed using Mummichog 2.0 on the 766 features identified by PLS-DA with a VIP ≥ 1.5. Overlapping features represents the number of metabolites enriched in the pathway, while pathway size describes the total number of metabolites in each pathway.