Table 1.
Clinical Characteristics | EVT Patients NIHSS ≤5 (n=446) |
EVT Patients NIHSS >5 (n=3,340) |
p value |
---|---|---|---|
Age (yrs), median (IQR) | 68±19 | 74±19 | <0.0001 |
Sex (male), % | 256 (57.4) | 1617 (48.4) | 0.0004 |
Ethnicity, % NH- white NH- black FL-Hispanic PR-Hispanic |
276 (61.8) 63 (14.1) 107 (23.9) 0 |
2022 (60.5) 517 (15.4) 788 (23.5) 13 (0.3) |
0.5 |
Medical Insurance, % Private* Medicare Medicaid/No Insurance** Unknown |
205 (45.9) 106 (23.7) 48 (10.7) 87 (19.5) |
1164 (34.8) 1175 (35.1) 303 (9.1) 698 (20.9) |
<0.0001 |
Vascular Risk Factor, % | |||
Current smoker, % | 78 (17.4) | 470 (14) | 0.05 |
Hypertension, % | 311 (69.7) | 2149 (64.3) | 0.02 |
Diabetes mellitus, % | 97 (21.7) | 780 (23.3) | 0.45 |
Dyslipidemia, % | 164 (36.7) | 1092 (32.6) | 0.08 |
Medical History, % | |||
Atrial fibrillation, % | 113 (25.3) | 1271 (38.0) | <0.0001 |
CAD/prior MI, % | 97 (21.7) | 694 (20.7) | 0.63 |
Previous stroke/TIA, % | 106 (23.7) | 665 (19.9) | 0.057 |
Arrival Time (%) On –hours Off- hours |
225 (50.4) 221 (49.5) |
1555 (46.5) 1785 (53.4) |
0.12 |
Hospital Arrival Time from Onset in minutes (median, IQR) |
138 (307) | 101 (219) | <0.0001 |
Patients based on arrival Time from Onset, % < 4.5 hrs 4.5– 6 hrs 6–12 hrs 12–24 hrs. |
297 (66.5) 36 (8.07) 69 (15.4) 44 (9.8) |
2525 (75.6) 247 (7.4) 377 (11.2) 191 (5.7) |
<0.0001 |
NIHSS (median), IQR | 3 (2) | 17 (9) | <0.001 |
Clinical Signs/symptoms, % | |||
Weakness | 203 (45.5) | 2152 (64.4) | <0.0001 |
Aphasia | 156 (34.9) | 1662 (49.7) | <0.0001 |
Altered level of Consciousness | 32 (7.1) | 838 (25.0) | <0.0001 |
Other Neurological Signs/symptoms | 88(19.7) | 778(23.2) | 0.09 |
Large Vessel Occlusion, % Yes Missing |
200(44.8) 246(55.2) |
1698(50.8) 1642(49.2) |
<0.0001 |
Mode of Arrival EMS, n (%) |
351 (78.7) |
3158 (94.5) |
<0.0001 |
Door to CT time, min (median, IQR) |
15 (19) |
13(14) |
<0.001 |
Door to CT time, % <25 min missing |
272 (61) 71 (15.9) |
2232 (66.8) 561 (16.8) |
0.0005 |
Intravenous Thrombolysis n, (%) | 135 (30.2) | 1409 (42.9) | <0.0001 |
Door to Needle Time, min (median, IQR) | 46 (36) | 42 (31) | 0.14 |
Door to Puncture Time, min (median, IQR) | 167 (70) | 115 (90) | <0.0001 |
CT to puncture time | 151 (175) | 105(83) | <0.0001 |
Hospital Characteristics | |||
Hospital Size (beds median/IQR) Small (<250) Mid (250–450) Large (>450) |
672 (316) 5 (1.1) 95 (21.3) 346 (77.6) |
716(431) 35 (1.05) 522 (15.6) 2783 (83.3) |
<0.0001 |
Academic hospital, % | 131 (29.3) | 1188 (25.5) | 0.009 |
Years in GWTG, median (IQR) | 12 (4) | 12 (2) | 0.08 |
Intravenous Alteplase treated patients/year (n) Low volume center (<20) High volume center (≥20) |
89(19.9) 357 (80.04) |
337 (10.09) 3003 (89.9) |
<0.0001 |
Stroke Center Type Comprehensive Stroke Center Primary Stroke Center Not primary/Comprehensive |
414 (92.8) 32 (7.17) 0 (0) |
3145 (94.1) 186 (5.57) 9(0.27) |
0.22 |
State Florida Puerto Rico |
446 (100) 0 (0) |
3327 (99.6) 13 (0.39) |
0.19 |
Region in Florida South East Central West Central North and Panhandle |
287 (64.35) 59 (13.23) 57 (12.78) 43 (9.64) |
1770(52.9) 452(13.5) 759(22.7) 346 (10.3) |
<0.0001 |
CAD= Coronary Artery Disease, MI=Myocardial Infarction. NH-White= Non-Hispanic White, NH-black= Non-Hispanic black. EMS= Emergency Medical Services.
Includes Private insurance, VA and other.
Includes Medicaid, self-pay and No insurance.