. Author manuscript; available in PMC: 2020 Aug 1.

Published in final edited form as: Ophthalmology. 2019 Feb 18;126(8):1076–1083. doi: 10.1016/j.ophtha.2019.02.011

Table 1.

Proportional Hazards Regression Analyses for the Association of Endothelial Cell Density with Late Endothelial Graft Failure

	N	Hazard Ratio (95% CI)	P^a
All Late Endothelial Graft Failures
Preoperative ECD^b	1223	1.25 (0.61, 2.57)	0.55
Late Endothelial Graft Failures after the 6 Month Visit
Preoperative ECD^b	966	1.37 (0.55, 3.43)	0.50
Change in ECD from Preoperative to 6 Months^c	966	2.09 (1.40, 3.12)	<0.001
ECD at 6 Months^b	996	2.74 (1.60, 4.67)	<0.001
Late Endothelial Graft Failures after the 12 Month Visit
Preoperative ECD^b	905	0.74 (0.21, 2.60)	0.64
Change in ECD from Preoperative to 12 Months^c	905	2.57 (1.31, 5.01)	0.006
ECD at 12 Months^b	935	2.95 (1.23, 7.05)	0.02

Based on a univariable Cox model.

Per 500 cells/mm² lower ECD

Per 500 cells/mm² decrease from the preoperative value

ECD = endothelial cell density

Preoperative endothelial images were analyzed by the reading center after lamellar dissection to create the donor lenticule by eye bank or prior to shipping for surgeon-prepared tissue