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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Am J Geriatr Psychiatry. 2019 Feb 7;27(8):794–805. doi: 10.1016/j.jagp.2019.02.002

TABLE 2.

Counts and Proportions of Potentially Inappropriate and Appropriate Antidepressant Initiation Medicare 5% Sample Claims Data (2012–2013)

Inappropriate Antidepressants (N = 579)
 Amitriptyline 104 (17.96)
 Clomipramine 2 (0.35)
 Desipramine 3 (0.52)
 Doxepin 32 (5.53)
 Imipramine 9 (1.55)
 Nortriptyline 35 (6.04)
 Paroxetine 394 (68.05)
Appropriate Antidepressants (N = 7,046)
 Bupropion 194 (2.75)
 Citalopram 1,552 (22.03)
 Desvenlafaxine 32 (0.45)
 Duloxetine 475 (6.74)
 Escitalopram 1,055 (14.97)
 Fluoxetine 361 (5.12)
 Fluoxetine/olanzapine 1 (0.01)
 Fluvoxamine 7 (0.10)
 Mirtazapine 1,042 (14.79)
 Nefazodone 2 (0.03)
 Phenelzine 0 (0.00)
 Selegiline 3 (0.04)
 Sertraline 1,543 (21.90)
 Tranylcypromine 0 (0.00)
 Trazodone 489 (6.94)
 Venlafaxine 265 (3.76)
 Vilazodone 25 (0.35)

Notes: Analysis based on 7,625 older adults with dementia and newly diagnosed major depression. At least one potentially inappropriate antidepressant was initiated by 579 (7.59%) older adults in this study sample.