Table 4.
Demographic, Clinical and Radiographic Characteristics of Included Patients, by Outcome.
| Variable, n (%) | Good Outcome (n=469) | Poor Outcome (n=286) | p |
|---|---|---|---|
| Age years, mean (SD) | 59 (12) | 65 (13) | <0.001 |
| Male Sex | 315/469 (67) | 159/286 (56) | 0.003 |
| Black | 43/469 (9) | 35/286 (12) | 0.20 |
| White | 98/469 (21) | 85/286 (30) | 0.008 |
| Hispanic | 34/469 (7) | 20/286 (7) | 0.76 |
| Hypertension | 357/456 (78) | 232/276 (84) | 0.01 |
| Diabetes | 70/462 (15) | 55/279 (20) | 0.34 |
| Hyperlipidemia | 103/446 (23) | 67/269 (25) | 0.92 |
| Congestive heart failure | 8/465 (2) | 12/282 (5) | 0.05 |
| Atrial fibrillation | 9/468 (2) | 14/280 (5) | 0.01 |
| Prior ischemic stroke | 65/468 (14) | 56/283 (19) | 0.05 |
| Smoker | 210/469 (45) | 129/286 (45) | 0.67 |
| On antihypertensive medication | 193/466 (41) | 158/284 (56) | <0.001 |
| Admission GCS, median (IQR) | 15 (14–15) | 14 (11–15) | <0.001 |
| Admission systolic BP mmHg, mean (SD) | 176 (24) | 175 (29) | 0.84 |
| Admission diastolic BP mmHg, mean (SD) | 114 (20) | 109 (21) | 0.005 |
| Admission INR | 0.98 (0.09) | 1.01 (0.14) | <0.001 |
| Thalamic location | 180/469 (38) | 144/286 (50) | <0.001 |
| ICH Volume mL, median (IQR) | 7.2 (3.7–12.8) | 13.7 (7.8–22.6) | <0.001 |
| PHE Volume mL, median (IQR) | 1.1 (0.6–2.1) | 1.7 (0.9–3.0) | <0.001 |
| IVH | 77/469 (16) | 130/286 (46) | <0.001 |
| Hematoma Expansion mL, mean (SD) | 1.5 (7.7) | 4.0 (14.0) | 0.001 |
| PHER mL/hr, median (IQR) | 0.01 (0.0–0.05) | 0.03 (0.0–0.1) | <0.001 |
Abbreviations: SD = standard deviation, GCS = Glasgow coma scale, BP = blood pressure, ICH = intracerebral hemorrhage, IQR = interquartile range