Table 5.
Association between PHER and Poor Outcome at 3 Months, by Location.
| Model | Overall (n=754) | Basal Ganglia (n=431) | Thalamus (n=323) | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | |
| PHER, unadjusted | 1.43 (1.24–1.67) | <0.001 | 2.05 (1.60–2.68) | <0.001 | 1.21 (0.85–1.73) | 0.30 |
| PHER, adjusted† | 1.14 (0.93–1.41) | 0.20 | 1.42 (1.05–1.97) | 0.03 | 1.02 (0.74–1.40) | 0.89 |
| Location*PHER Interaction Term, adjusted† | 1.54 (1.15– 3.18) | 0.01 | - | - | - | - |
†
Model adjusted for age, sex, admission GCS, admission ICH volume (natural log transformed), presence of intraventricular hemorrhage, volume of hematoma expansion, and treatment group.
Abbreviations: PHER = perihematomal edema expansion rate, OR = odds ratio, CI = confidence interval