. Author manuscript; available in PMC: 2019 Aug 1.

Published in final edited form as: J Gastrointest Surg. 2019 Jan 22;23(8):1604–1613. doi: 10.1007/s11605-018-04084-x

Table 4:

Literature review of post-pancreatectomy endocrine and exocrine insufficiency

Study	n =	Study Type	Type of pancreatectomy	Endocrine Insufficiency	Exocrine Insufficiency
Cherif et al.⁵	118	Prospective, controlled cohort	PD = 28 DP = 27 PSP = 63	6 (21.4%) 1 (3.7%) 3 (4.8%)	16 (57.1%) 2 (7.4%) 2 (3.2%)
Falconi et al.⁶	135	Prospective, controlled cohort	PD = 51 DP = 50 AR = 34	9 (17.6%) 7 (14.0%) 1 (2.9%)	17 (33.3%) 9 (18.0%) 0 (0%)
Lim et al.¹³	227	Prospective, case series	PD = 159 DP = 63 Enucleation = 5	28/178 without pre- operative endocrine insufficiency (15.7%)	94/214 without pre- operative exocrine insufficiency (43.9%)
Halloran et al.¹⁶	40	Prospective, cohort	PD = 37 DP = 3	-	30/39 at 6 weeks (76.9%) 19/22 at 1 year (86.4%)
Hirata et al.¹⁸	167	Retrospective, cohort	PD = 100 DP = 67	68 (40.7%)	-
Kwon et al.²¹	229	Retrospective, cohort	PD = 94 DP = 118 CP = 17	52 (22.7%)	-
Wu et al.³³	3914	Retrospective, population based	PD = 3914	632 (16.1%)	-
Ferrara et al.³⁴	564	Retrospective, cohort	PD = 564	22 (3.9%)	-

Orfanidis et al.³⁵	41	Retrospective, cohort (prospective interviews)	PD = 41	8 (19.5%)	5 (12.2%)
Elliott et al.³⁶	1165	Retrospective, population based	PD = 692 DP = 473	274/678 without pre- operative endocrine insufficiency (40.4%)	235/678 without pre- operative endocrine insufficiency (34.7%)

PD – pancreaticoduodenectomy, DP– distal pancreatectomy, PSP – pancreas sparing pancreatectomy (enucleation and central pancreatectomy), CP – central pancreatectomy, AR – atypical resection