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. 2019 Jul 22;9:10542. doi: 10.1038/s41598-019-46896-0

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparative proteomic and overall composition of different connective tissues. (a) Relative abundance of ECM proteins derived from studies that investigated the large numbers of proteins or complete proteomes in articular cartilage, skeletal muscle, tendon, ligament, and bone. For articular cartilage, skeletal muscle, ligament, and bone the data are from a single study; for tendon, relative abundance of top 10 proteins identified by both studies was averaged. (b) Relative quantity of whole tissue constituents in articular cartilage, skeletal muscle, ligament, tendon, bone, adipose tissue, and IVD.