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. 2019 Jul 22;9:10552. doi: 10.1038/s41598-019-47156-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(a) Silicone phantom and USF signal measurement setup. (b) Scheme of the three selected time-gated window (i.e., mode 1, mode 2, and mode 3) for the three cases: the left panel represents Case 1 in which both the background and the USF signal had similar lifetimes and decayed at a similar speed; the right panel represents Case 2 and 3 in which the background had a short lifetime and decayed fast while the USF signal had a long lifetime and decayed slowly. (c) USF images acquired at the three modes for the three cases.