Table 1.
Regulation of putative candidate genes and corresponding KEGG numbers for size regulation in polyps with INSR-KD or FoxO-KD and after temperature shift
| Temperature | INSR-KD | FoxO-KD | ||||||
|---|---|---|---|---|---|---|---|---|
| Gene | KEGG No. | 12 °C vs. 18 °C | 18 °C vs. 22 °C | ecto/endo 18 °C | ecto/endo 12 °C | ecto 18 °C | ecto/endo 18 °C | |
| TGF-β | ACV (INHB) | K04667 | ↓ | ↓ | ↓ | ↓ | ↓ | |
| ACVR2A | K04670 | ↑ | ||||||
| Cer-1 | K01645 | ↓ | ↓ | ↓ | ||||
| DAN (GREM) | K19558 | ↑ | ||||||
| DAN (NBL1) | K19558 | ↑ | ↑ | ↑ | ||||
| TGF-β2 | K13376 | ↑ | ↑ | ↓ | ↓ | |||
| THBS1 | K16857 | ↑ | ↑ | ↓ | ↓ | |||
| Wnt | Wnt11 | K01384 | ↑ | ↑ | ↑ | |||
| FZD1/7 | K02432 | ↓ | ↓ | ↓ | ||||
| Notum | K19882 | ↓ | ↓ | |||||
| Others | CALM | K02183 | ↑ | ↓ | ↑ | |||
| Casp3 | K02187 | ↑ | ↓ | ↑ | ||||
| Casp7 | K04397 | ↑ | ||||||
| FGF-C | K04358 | ↑ | ↑ | ↑ | ||||
| FGFR1 | K04362 | ↑ | ↑ | |||||
| FLNA | K04437 | ↑ | ↑ | ↑ | ||||
| Notch | K02599 | ↓ | ↓ | ↓ | ↑ | |||
| K-ras | K07827 | ↓ | ↓ | ↓ | ↓ | |||
| R-ras | K07829 | ↓ | ↓ | ↑ | ||||