Table 2.
Strain | Teixobactin | 20 | 21 | 22 | 24 | 25 | 26 | Ampicillin |
---|---|---|---|---|---|---|---|---|
E. faecalis ATCC29212 | 1 | 0.25 | 0.5 | 0.25 | 0.25 | – | 0.375 | 1 |
E. faecalis TH4130 | 0.5 | 0.0625 | 0.125 | 0.125 | 0.25 | – | 0.0625 | 16 |
E. faecalis TH4132 | 0.5 | 0.187 | 0.5 | 0.187 | 0.75 | – | 0.187 | 1 |
E. faecalis TH4126 | 0.25 | 0.0625 | 0.187 | 0.125 | 0.25 | – | 0.0625 | >32 |
VRE TH4939 | 0.25 | 0.125 | 0.187 | 0.25 | 0.5 | – | 0.09 | >32 |
VRE TH4937 | 0.375 | 0.09 | 0.09 | 0.125 | 0.187 | – | 0.0625 | >32 |
MRSA BAA-1695 | 0.25 | 0.125 | 0.09 | 0.125 | 0.25 | – | 0.09 | >32 |
MRSA TH4115 | 0.5 | 0.25 | 0.5 | – | – | 0.25 | 0.25 | 32 |
S. aureus TH4112 | 0.25 | 0.125 | 0.125 | 0.125 | 0.25 | 0.187 | 0.125 | 0.5 |
S. pneumoniae D39 | <0.0625 | <0.0625 | – | – | – | <0.0625 | <0.0625 | 0.125 |
S. aureus ATCC29213b | 0.22 ± 0.06 | 0.13 ± 0.07 | – | – | – | – | – | 2 |
MRSA ATCC33591b | 0.11 ± 0.03 | 0.07 ± 0.03 | – | – | – | – | – | >16 |
S. agalactiaeATCC BAA-611 | <0.0625 | <0.0625 | – | – | – | – | – | 0.125 |
S. pyogenes ATCC 19615 | <0.0625 | <0.0625 | – | – | – | – | – | 0.125 |
Source data are provided as a Source Data file
aThe assay was done three times to confirm results (n = 3)
bData represent five independent experiments ± s.d. (n = 5)